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Zebrafish

7th European Zebrafish Meeting

Edinburgh, Scotland 5th - 9th July 2011

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Scientific Programme

Meeting Blogging Policy

The 7th European Zebrafish Meeting aims to retain a 'small meeting' feel and encourages scientists to speak about new and unpublished data.  There will be editors and journalists attending, as well as scientists who might be contributing to blogs.  We ask all journalists and bloggers that if they plan to report directly specific details of any of the presentations, they first seek the approval of the presenter.

If you do want to report or blog about details of the presentations at the meeting, please speak to the conference organisers, In Conference.

To print a copy of the programme click here

Tuesday 5th July 2011

Time Sessions Location
09:00 - 17:00
Working Zebrafish Genome Resources Workshop (Wellcome Trust Sanger Institute)

This is NOT included in the main meeting registration, delegates must register seperatly through the sanger website, places are limited.  For further details about this workshop and registration please click on the link below:
http://www.sanger.ac.uk/resources/talksandtraining/opendoor/edinburgh.html

Ochil Suite
12:00 - 19:30
Registration & Information Desk
Strathblane Hall
13:00 - 17:00
Zebrafish Husbandry Workshop
In Association with UCL, ZIRC, ZHA and BAZH
This is an open door workshop for delegates registered for the 7th European Zebrafish Meeting
Places will be on a first come first served basis
For further details please click here
Lomond Suite
13:00 - 19:30
Crèche
Carrick Suite
15:00 - 18:00
Speaker Preview
Harris 1
18:00 - 19:30
Welcome Reception
Cromdale Hall

Wednesday 6th July 2011

Time Sessions Location
08:00 - 20:00
Registration & Information Desk
Strathblane Hall
08:00 - 17:00
Speaker Preview
Harris 1
08:30 - 20:00
Crèche
Carrick Suite
09:00 - 09:15
Opening Remarks
Local Organising Committee
Pentland Suite
09:15 - 11:00
Plenary Session 1 - Technology
Chair: Derek Stemple

09.15-09.30

PL1-1

The Zebrafish Mutation Project (ZMP): Whole exome sequencing of mutagenised zebrafish to identify a non-sense allele in every protein coding gene

Ross Kettleborough

 

09.30-09.45

PL1-2

Generation of a genome-wide knockout library in zebrafish

Shawn Burgess

 

09.45-10.00

PL1-3

From cells to tissues - high resolution cell lineage and clonal analysis in the developing zebrafish brain

Qiling Xu

 

10.00-10.15

PL1-4

Polysome profiling reveals novel translational control mechanisms during zebrafish development

Todd Evans

 

10.15-10.30

PL1-5

Photocontrol of protein activity at the single cell level

Carole Gauron

 

10.30-10.45

PL1-6

Regulating gene activity in transgenic zebrafish with the Neurospora Q system

Marnie E. Halpern
Pentland Suite
10:00 - 20:00
Exhibition & Poster Area Open
Comdale & Strathblane Hall
10:45 - 11:30
Tea / Coffee / Exhibition / Posters
Cromdale & Strathblane Hall
11:30 - 13:00
Plenary Session 2 - Neurogenesis/Gilogenesis
Chair: Jon Clarke

11.30-11.45

PL2-1

Specification and role in development of hindbrain rhombomere boundaries

Javier Terriente

 

11.45-12.00

PL2-2

Vesicular transport of DeltaD ligands in the embryonic neuroepithelium: A novel imaging approach to study the endocytic trafficking of endogenous signaling molecules in intact living zebrafish

Maximilian Fürthauer

 

12.00-12.15

PL2-3

Generation of neuronal diversity by ath5-expressing progenitors in the zebrafish

Shahad Albadri

 

12.15-12.30

PL2-4

Exploring a role for heterochrony and orientation of divisions during specification of PhR subtypes

Elise Cau

 

12.30-12.45

PL2-5

Light and melatonin schedule neuronal differentiation in the habenular nuclei 

Joshua Gamse

 

12.45-13.00

PL2-6

Live imaging reveals cell-cell interactions that regulate central nervous system myelination

Tim Czopka


Pentland Suite
13:00 - 15:00
Buffet Lunch / Exhibition / Poster Viewing Session A
(Poster Board Numbers P1-1 to P1-202)
Cromdale & Strathblane Hall
13:30 - 14:30
Open Zebrafish Atlases Discussion
Open door discussion group, places will be limited and will be on a first come first served basis
Ochil Suite
13:30 - 14:30
COST - Working Group 1 Meeting
Harris 2
13:40 - 14:20
Satellite Symposium

Hosted by Tecniplast (Platinum Sponsor)

The i-Spawn: A Novel Group Spawning Chamber for Zebrafish

Isaac Adatto

Christian Lawrence

Marco Brocca
Lomond Suite
15:00 - 17:00
Parallel Symposium 1 - Muscle, Skin and Connective Tissue
Chair: Phil Ingham

15.00-15.15

O1-1

Molecular toolbox for muscle cell repair

Urmas Roostalu

 

15.15-15.30

O1-2

Developmental transition of motility from slow muscle-mediated coilings to fast muscle-mediated escape response in zebrafish

Hiromi Hirata

 

15.30-15.45

O1-3

The zebrafish mutant mi34 is necessary for normal excitation contraction coupling in skeletal muscle

Eric Horstick

 

15.45-16.00

O1-4

Col22a1 depletion in zebrafish leads to severe muscle dystrophy by disruption of myotendinous junction 

Florence Ruggiero

 

16.00-16.15

O1-5

fused somites (tbx24) regulates paraxial mesoderm cell fate

Stephen Devoto

 

16.15-16.30

O1-6

Eat or be eaten: In vivo lineage tracing identifies oesophageal and sternohyoid striated muscle as novel Pax3b-dependent somite-derived voluntary muscles that improve swallowing

Simon Hughes

 

16.30-16.45

O1-7

The kindlin-1del565 mutant is a unique model for studying kindler syndrome in vivo, revealing novel functions of kindlin-1.

Ruben Postel

 

16.45-17.00

O1-8

Adult zebrafish as a model for epidermal wound healing 

Rebecca Richardson

Pentland Suite
15:00 - 16:00
Parallel Symposium 2A - Axon Guidance and Circuit Formation

Chair: Martin Meyer

15.00-15.15

O2A-1

Sim1/Arnt2 transcription factors contribute to hypothalamo-spinal axon guidance by regulating Robo2 activity via a Robo3 dependent mechanism

Jörn Schweitzer

 

15.15-15.30

O2A-2

Retinal axon trajectories in the optic tract are topographically edited by a heparan sulfate-dependent mechanism

Fabienne Poulain

 

15.30-15.45

O2A-3

Zebrafish Fidgetin-like 1 controls spinal motor axon guidance through the regulation of microtubule dynamics

Coralie Fassier

 

15.45-16.00

O2A-4

Notum 2 a novel regulator of motor axon guidance

Jorge Cantu

Lomond Suite
16:00 - 17:00
Parallel Symposium 2B - Behaviour

Chair:  Stephan Neuhauss


16.00-16.15

O2B-1

Genetic dissection of the hindbrain by the Gal4-UAS system

Kazuhide Asakawa

 

16.15-16.30

O2B-2

MANF regulates the development of the catecholaminergic system in zebrafish

Pertti Panula

 

16.30-16.45

O2B-3

Behavioural lateralisation and avoidance behaviours

K. Anukampa Barth

 

16.45-17.00

O2B-4

Visual behavior testing in larval and adult zebrafish

Stephan Neuhauss

Lomond Suite
17:00 - 17:30
Tea / Coffee / Exhibition / Posters
Cromdale & Strathblane Hall
17:30 - 18:30
Keynote Lecture 1 - Of bottlenecks and shortcuts: How to make neurons in C.elegans
(Hosted by David Lyons)

 

Speakers:
Professor Oliver Hobert
HHMI Investigator
Pentland Suite
18:30 - 20:00
Poster Viewing Session B
(Poster Board Numbers P1-1 to P1-202)
Cromdale & Strathblane Hall
18:30 - 20:00
COST - Working Group 3 Meeting
Harris 2

Thursday 7th July 2011

Time Sessions Location
08:00 - 18:00
Registration & Information Desk
Strathblane Hall
08:00 - 17:00
Speaker Preview
Harris 1
08:30 - 18:00
Crèche
Carrick Suite
09:00 - 11:00
Plenary Session 3 - Early Development and Patterning
Chair: Corinne Houart

09.00-09.15

PL3-1

The zebrafish maternal-effect mutant motley reveals a novel role for the chromosomal passenger complex in interphase f-actin dynamics and germ plasm localization

Sreelaja Nair

 

09.15-09.30

PL3-2

Dynamic Microtubules at the Vegetal Cortex of Early Zebrafish Embryos

Long Tran

 

09.30-09.45

PL3-3

Gpr125 - A novel planar cell polarity pathway component in zebrafish

Florence Marlow

 

09.45-10.00

PL3-4

Systematic investigation of vertebrate synexpression groups

Robert Reinhardt

 

10.00-10.15

PL3-5

Mesogenin throws the switch that converts mesodermal progenitors into paraxial mesoderm

Rita Fior

 

10.15-10.30

PL3-6

Visualizing in vivo notch- and cell cycle-mediated synchronization of the zebrafish segmentation clock

Emilie Delaune

 

10.30-10.45

PL3-7

Translating pattern into shape: a role for Wnt signaling and Zic transcription factors during neurulation.

Yevgenya Grinblat

 

10.45-11.00

PL3-8

Boundaries of ephrin activity in the anterior neural plate are required for the correct morphogenesis of the forebrain

Florencia Cavodeassi

Pentland Suite
10:00 - 18:00
Exhibition & Poster Area Open
Cromdale & Strathblane Hall
11:00 - 11:30
Tea / Coffee / Exhibition / Posters
Cromdale & Strathblane Hall
11:30 - 13:00
Plenary Session 4 - Screens
Chair: Len Zon

11.30-11.45

PL4-1

High-throughput zebrafish imaging, surgery, and screening at cellular resolution

Tsung-Yao Chang

 

11.45-12.00

PL4-2

Developing a therapeutic model for TARDBP mutations in ALS using zebrafish

Alexandra Lissouba

 

12.00-12.15

PL4-3

Inhibitors of developmental angiogenesis in zebrafish effectively inhibit pathological ocular neovascularisation in mice

Breandan Kennedy

 

12.15-12.30

PL4-4

The enhancer disruption (ED) screen in zebrafish

Jose Bessa

 

12:30-12:45

PL4-5

Fast mapping of a mutation affecting pancreas development by high-throughput sequencing

Marianne Voz

 

12:45-13:00

PL4-6

The Sanger Institute zebrafish mutation project: Functional annotation of the zebrafish genome

Elisabeth Busch-Nentwich

Pentland Suite
13:00 - 15:00
Bag Lunch / Exhibition / Poster Viewing Session C
(Poster Board Numbers P2-1 to P2-241)
Cromdale & Strathblane Hall
13:15 - 14:45
Chemical Biology Workshop

Chair: Len Zon

13:15-13:25 

Introduction - Len Zon

 

13:25 - 13:45 

Short presentations - new technology


13:45 - 14:30

Discussion lead by Len Zon

Special focus on screen design, chemical libraries, compound follow-up and target ID

 

14:30 - 14:45

Summary and conclusions - Len Zon

Lomond Suite
13:30 - 15:00
Advanced Live Cell Imaging & Quantitative Image Analysis

Workshop by PerkinElmer

This is NOT included in the main meeting registration, delegates must register seperatly through the link below, Registration is free but space is limited, please reserve your place here

 

The session will consist of:

A short introduction to PerkinElmer’s Cellular Imaging & Analysis Portfolio – tools for image capture, data management and image analysis.

A live demonstration of Volocity® – high performance, 3D image analysis software for fluorescence image data.

 

Ochil Suite
13:30 - 15:00
COST - Working Group 2 Meeting
Harris 2
15:00 - 16:00
Parallel Symposium 3 - High Throughput Analyses of Early Development

Chair: Corrine Houart

15.00-15.20

O3-1

Identification of maternal and paternal mRNA's during the maternal to zygotic transition

Steve Harvey

 

15.20-15.40

O3-2

Transcriptomic and epigenetic dynamics before and during zebrafish zygotic genome activation

Peter Aleström

 

15.40-16.00

O3-3

Transcription initiation and mRNA degradation mechanisms at the mid blastula transition are revealed by characterization of the developmental promoterome

Ferenc Müller


Pentland Suite
15:00 - 16:00
Parallel Symposium 4 - Comparative Developmental Biology
Chair: Manfred Scharti

15.00-15.15

O4-1

The role of fanconi Anemia/BRCA genes in zebrafish sex determination

John H. Postlethwait

 

15.15-15.30

O4-2

Identification of target genes for the male sex determining gene dmrt1bY in medaka

Manfred Schartl

 

15.30-15.4

O4-3

A cis-regulatory signature for anterior nervous system genes

Yan Jaszczyszyn

 

15.45-16.00

O4-4

Discovery of novel evolutionarily conserved direct targets of Pax6

Pedro Coutinho


Lomond Suite
16:00 - 16:30
Tea/Coffee / Exhibition / Posters
Cromdale & Strathblane Hall
16:30 - 18:00
Parallel Symposium 5 - Organogenesis
Chair: Elke Ober

16:30-16:45

O5-1

EphrinB/EphB signalling controls morphogenesis of endoderm and lateral plate mesoderm in zebrafish

Jordi Cayuso

 

16:45-17:00

O5-2

Wnt4a and Wnt11r coordinate branching morphogenesis of endodermal pouch epithelia by controlling cell migration and junctional ALCAM localization

Chong Pyo Choe

 

17.00-17.15

O5-3

Wnt/B-catenin signaling regulates ciliogenesis via direct modulation of ciliogenic transcription factor foxj1a

Xueying Lin

 

17.15-17.30

O5-4

The role of scribble in the notochord and vertebral column formation

Jolanta Topczewska

 

17.30-17.45

O5-5

Control of cell motility by the RNA-binding protein dead end

Erez Raz

 

17.45-18.00

O5-6

Estrogen exhibits a biphasic role on liver development mediated by esr2 and affects liver regeneration

Wolfram Goessling

Pentland Suite
16:30 - 18:00
Parallel Symposium 6 - Neural Crest
Chair: Robert Kelsh

16:30-16:45

O6-1

Neuronal neuregulin 1 type III directs schwann cell migration

William Talbot

 

16:45-17:00

O6-2

Skeletogenic potential of zebrafish cranial and trunk neural crest

Shannon Fisher

 

17.00-17.15

O6-3

Different modes of cell behavior generate diverse shapes in the craniofacial skeleton

April DeLaurier

 

17.15-17.30

O6-4

The role of intraflagellar transport genes in craniofacial morphogenesis

Pamela C. Yelick

 

17.30-17.45

O6-5

Melanocyte self-duplication contributes to pigmentation patterning and is enhanced in regeneration

Kerrie Taylor

 

17.45-18.00

O6-6

An iterative genetic and dynamical modelling approach identifies novel features of the gene regulatory network underlying melanocyte development

Robert N. Kelsh

Lomond Suite
18:00 - 19:00
Delegates to make their way to Edinburgh Castle
19:00 - 20:30
Reception
Edinburgh Castle

Friday 8th July 2011

Time Sessions Location
08:00 - 18:00
Registration & Information Desk
Strathblane Hall
08:00 - 17:00
Speaker Preview
Harris 1
08:30 - 18:00
Crèche
Carrick Suite
09:00 - 10:30
Parallel Symposium 7 - Regeneration and Stem Cells
Chair: Thomas Becker

09.00-09.15

O7-1

Profound differences in reactive gliosis after stab wound injury of the adult zebrafish telencephalon accompany long-term survival of additionally generated neurons and the absence of scar formation

Jovica Ninkovic

 

09.15-09.30

O7-2

Regeneration of the adult zebrafish brain: new neurons from radial glia-type progenitor cells

Michael Brand

 

09.30-09.45

O7-3

Müller glial-dependent regeneration of photoreceptors in the light-damaged retina requires tumor necrosis factor-alpha 

David Hyde

 

09.45-10.00

O7-4

Dopamine signaling from the brain augments spinal motor neuron generation during development and adult regeneration via hedgehog pathway activation

Catherina G. Becker

 

10.00-10.15

O7-5

Extensive scar formation and regression during heart regeneration after cryoinjury in zebrafish

Juan Manuel González-Rosa

 

10.15-10.30

O7-6

Bone regenerates via dedifferentiation of osteoblasts in the zebrafish fin

Franziska Knopf

Pentland Suite
09:00 - 10:30
Parallel Symposium 8 - Infection and Immunity
Chair: Philippe Herbomel

09.00-09.15

O8-1

The haematopoietic stem/progenitor cell pool responds to infection by expanding and enhancing its commitment to the neutrophil lineage through a mechanism dependent on inducible nitric oxide

Chris Hall

 

09.15-09.30

O8-2

High throughput screening of disease in zebrafish and carp

Herman Spaink

 

09.30-09.45

O8-3

What really happens during Cryptococcus infection? A zebrafish model of infection and immunity cell biology in vivo

Simon Johnston

 

09.45-10.00

O8-4

Altered intestinal microbial composition and innate immunity in Rag1-/- zebrafish

Sylvia Brugman

 

10.00-10.15

O8-5

Live imaging the role of key cytoskeletal regulators on immune cell behaviours in zebrafish larvae

Rebecca Jones

 

10.15-10.30

O8-6

Macrophage behaviour during inflammation and infection  

Felix Ellett

Lomond Suite
10:00 - 16:30
Exhibition & Poster Area Open
Cromdale & Strathblane Hall
10:30 - 11:00
Tea / Coffee / Exhibition / Posters
Cromdale & Strathblane Hall
11:00 - 12:30
Parallel Symposium 9 - Cancer
Chair: Joan Heath

11.00-11.15

O9-1

Tumorigenesis in zebrafish: TOR is not enough?

Kevin Ess

 

11.15-11.30

O9-2

Oncogenic ras affects polarity and cell divisions of telencephalic neuroepithelial cells in a zebrafish model of malignant glioma

Marina Mione

 

11.30-11.45

O9-3

Zebrafish nervous system microenvironment promotes phenotypic reprogramming of Glioblastoma derived cells through Wnt pathway activation

Elena Rampazzo

 

11.45-12.00

O9-4

Inducible and repressible oncogene-addicted hepatocellular carcinoma in Tet-on and mifepristone-inducible transgenic zebrafish

Zhiyuan Gong

 

12.00-12.15

O9-5

VEGFR targeting elicits metastasis by modification of myeloid cells in a zebrafish xenograft model

B.Ewa Snaar-Jagalska

 

12.15-12.30

O9-6

SUV39H1 suppresses rhabdomyosarcoma formation in zebrafish

Colleen Albacker

Pentland Suite
11:00 - 12:30
Parallel Symposium 10 - Sensory Systems
Chair: Rainer Friedrich and Darren Gilmour

11.00-11.15

O10-1

Lef1-dependent Wnt/ß-catenin signalling drives the proliferative engine that maintains tissue homeostasis during lateral line development

Rodrigo Young

 

11.15-11.30

O10-2

A Cadherin23-Harmonin-Ift88 module is required for trafficking and localization of usher proteins in the zebrafish ear and eye

Bernardo Blanco-Sanchez

 

11.30-11.45

O10-3

Origin of inner ear hair cells: morphological and functional differentiation from ciliary cells into hair cells in zebrafish inner ear

Masashi Tanimoto

 

11.45-12.00

O10-4

Piezo2a is required for mechanically-gated currents in zebrafish light-touch mechanoreceptors

Sean Low

 

12.00-12.15

O10-5

Visual modulation of audiomotor response via hypothalamic dopaminergic neurons

Jiulin Du

 

12.15-12.30

O10-6

Mapping motion-sensitive inputs into the zebrafish optic tectum

Nikolas Nikolaou

Lomond Suite
12:30 - 14:00
Buffet Lunch / Exhibition / Poster Viewing Session D
(Poster Board Numbers P2-1 to P2-241)
Cromdale & Strathblane Hall
12:45 - 13:45
COST - Working Group 4 Meeting
Harris 2
14:00 - 16:00
Plenary Session 5 - Cardio-Vascular Development & Hematopoiesis
Chair: Roger Patient

14.00-14.15

PL5-1

Genesis and cell fate decisions of blood stem cells in zebrafish embryos

Roger Patient

 

14.15-14.30

PL5-2

Scl isoforms act downstream of etsrp to specify angioblasts and definitive hematopoietic stem cells

Xi Ren

 

14.30-14.45

PL5-3

Metabolism-induced reactive oxygen species (ROS) and hif1a stimulation control the induction and expansion of hematopoietic stem cells

Trista North

 

14.45-15.00

PL5-4

Clonal analysis of hematopoietic stem and progenitor cells in the zebrafish

David Stachura

 

15.00-15.15

PL5-5

Semaphorin-PlexinD1 signaling represses angiogenic potential

Jesús Torres-Vázquez

 

15.15-15.30

PL5-6

Hematopoietic cell lineage analysis from ventrolateral mesoderm through the draculin regulatory region

Christian Mosimann

 

15.30-15.45

PL5-7

Transmembrane protein 2 (tmem2) is required to regionally restrict atrioventricular canal boundary and endocardial cushion development

Kelly Smith

 

15.45-16.00

PL5-8

The genetic program regulating cardiac septation is present in the zebrafish heart

Daniela Panakova

Pentland Suite
16:00 - 16:30
Tea / Coffee / Exhibition / Posters
Cromdale & Strathblane Hall
16:30 - 18:00
Community Session & Poster Prizes
Pentland Suite
18:00 - 18:30
Free Time
18:00 - 18:30
Delegates to make their way to St Mary's Cathedral
18:30 - 19:30
Music Concert
St Mary's Cathedral

Saturday 9th July 2011

Time Sessions Location
08:00 - 11:00
Speaker Preview
Harris 1
08:30 - 12:00
Registration & Information Desk
Strathblane Hall
08:30 - 13:00
Crèche
Carrick Suite
09:00 - 11:00
Plenary Session 6 - Disease Models
Chair: Freek van Eeden

09.00-09.15

PL6-1

Modulation of muscle fibre integrity by manipulation of laminin/Integrin complexes

Peter Currie

 

09.15-09.30

PL6-2

Zebrafish mutants that model human osteoarthritis

Chrissy Hammond

 

09.30-09.45

PL6-3

Zebrafish as a model for compensatory β cell hyperplasia

Wenbiao Chen

 

09.45-10.00

PL6-4

Using zebrafish as a tool to define function of16p11.2 autism genes

Sunny Gupta

 

10.00-10.15

PL6-5

Silencing of RhoA nucleotide exchange factor, ARHGEF3 reveals its unexpected role in iron uptake

Ana Cvejic

 

10.15-10.30

PL6-6

Lipoprotein oxidation and formation of vascular lesions in hypercholesterolemic zebrafish  

Yury Miller

 

10.30-10.45

PL6-7

Aberrant phosphatidylinositol synthesis leads to hepatocellular ER stress and steatosis in cdipt-deficient zebrafish: a model for non-alcoholic fatty liver disease

Prakash Thakur

 

10.45-11.00

PL6-8

Notch signaling is required for mast cell development in the zebrafish and may represent a novel therapeutic strategy in human systemic mastocytosis

Jason Berman

Pentland Suite
11:00 - 11:30
Tea / Coffee
Strathblane Hall
11:30 - 12:30
Keynote Lecture 2 - The p53 pathway in Zebrafish
(hosted by Liz Patton)
Speakers:
Professor Sir David Lane
Director Cancer Research UK Transformation
Pentland Suite
12:30 - 13:00
Closing Remarks & 2013 Meeting
Pentland Suite
13:15 - 17:00
COST - Management Committee Meeting
Ochil Suite